Disprin Direct Chewables - fast and effective. Disprin Direct Chewables don't need to be taken with water, so they can be taken anywhere. They are absorbed quickly to bring rapid, effective, temporary relief from pain associated with: Headaches & Migraine Headaches. Rheumatic and Arthritic Pain. Neuralgia (Nerve Pain). Toothaches. Cold & Flu Symptoms. Sore Throats. Period Pain. Fibrositis. Reduces Inflammation. Associated with back and muscular pain, and strains and sprain. Reduces Fever. Disprin Direct Chewables are Aluminum free.